Evergreen
Published June 1, 2026 | Version v1
Journal article Open

Exploring the Impact of Inhibitory Compounds and Acid Resistance in Non-Conventional Yeast for Xylitol Production

Authors/Creators

  • 1. Research Center for Biosystematics and Evolution, National Research and Innovation Agency (BRIN), Jalan Raya Bogor Km. 46, Bogor 16911, Indonesia
  • 2. Research Center for Applied Microbiology, National Research and Innovation Agency (BRIN), Jalan Raya Bogor Km. 46, Bogor 16911, Indonesia
  • 3. Department of Biology, Faculty of Mathematics and Natural Sciences, IPB University, Jalan Agatis Kampus IPB Dramaga, Bogor 16680, Indonesia
  • 4. Biotech Center, Collaborative Research Center, IPB University, Faculty of Mathematics and Natural Sciences, Bogor 16680, Indonesia

Contributors

Contact person:

  • 1. Research Center for Biosystematics and Evolution, National Research and Innovation Agency (BRIN), Jalan Raya Bogor Km. 46, Bogor 16911, Indonesia

Description

Inhibitory chemical compounds (ICCs) as by-products and acidic conditions during plant biomass pretreatment were inhibited microbial fermentation. This study aimed to select and characterize the inhibitory and acid-resistant chemical compounds of unique yeasts capable of producing xylitol. Meyerozyma guilliermondii InaCCY65 was selected as a potential candidate for bioconversion of lignocellulose to xylitol. This strain can grow in various hydrolysates in acidic pH and still produce xylitol. The optimum temperature and pH of InaCCY65 for producing xylitol are 30°C and pH 4.5. This strain was tolerating ICC and capable of detoxifying ICCs. The results will provide new technology to produce xylitol with yeast that are robust and tolerant to ICC and acidic conditions.

Notes

Published in Evergreen, Volume 13, Issue 02. Citation formats available via DOI link.

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Other: https://citation.crossref.org/?doi=10.5109/7434180 (URL)