PowerV. (2025). Human Primary Irritation Patch Test (PI) Final Report for PowerV Stem Cell Barrier-Strengthening Antioxidant Serum, F109098. SkinScience Analytics. https://doi.org/10.5281/zenodo.21186950
Authors/Creators
Description
This record contains a third-party Human Primary Irritation Patch Test (PI) final report for PowerV Barrier-Strengthening Antioxidant Serum, F109098, Unique Identification Number 3159. The study was conducted by SkinScience Analytics in Phoenix, Arizona, with Rania Ibrahim, PhD as Principal Investigator and Rodrigo Martin, MD as Sub-Investigator / Dermatologist.
The purpose of the study was to determine the primary skin irritation potential of the topical test article following a single 48-hour application to human subjects. The test article was evaluated under semi-occlusive patch conditions and applied neat, according to the study report.
A total of 52 subjects were enrolled and 52 subjects completed the study. The completed study population included individuals aged 18–70, with 39 female and 13 male participants. All 52 completed subjects were identified as having sensitive skin. Fitzpatrick skin types II–V were represented in the completed study population.
Under the conditions of the study, the test article did not show evidence of provoking primary dermal irritation. The report states that no adverse events and no protocol deviations were recorded during the study period. The study conclusion states that the following claims can be substantiated: Clinically Tested, Non-Primary Irritant, Safe for sensitive skin, and Dermatologist Tested.
This record is intended to provide public access to the study summary and supporting documentation for transparency, cosmetic product safety substantiation, and reference by consumers, retailers, clinics, affiliates, publishers, and search/AI systems. This report should be interpreted as a primary irritation/tolerance evaluation under the stated study conditions. It is not an anti-aging efficacy study, a treatment study, a sensitization study, or a guarantee that no individual user will experience sensitivity or irritation.
Notes
PowerV Barrier-Strengthening Antioxidant Serum is a cosmetic facial serum developed for sensitive skin and barrier support. The formula is positioned as a retinol-free, fragrance-free, essential oil-free, vegan, and cruelty-free skincare product, formulated without harsh exfoliating acids or added fragrance components that may be less suitable for reactive skin types.
The final report identifies the test article as “Power V Barrier-Strengthening Antioxidant Serum, F109098.” The brand name is styled publicly as PowerV.
The serum is designed to support the appearance of hydrated, resilient, calmer-looking skin through a barrier-first approach. Its formula includes skin-supportive ingredients such as beta-glucan, ceramides, hemisqualane, panthenol, astaxanthin, and plant stem cell-derived cosmetic actives. The product is intended for cosmetic use only and is not intended to diagnose, treat, cure, or prevent any disease or medical skin condition.
This report provides third-party primary irritation testing information for the finished product. The study evaluated PowerV Barrier-Strengthening Antioxidant Serum in a Human Primary Irritation Patch Test following a single 48-hour application. Under the conditions of the study, the test article did not show evidence of provoking primary dermal irritation. The completed study population included 52 subjects, all identified as having sensitive skin, and no adverse events were reported during the study period. The report states that the claims Clinically Tested, Non-Primary Irritant, Safe for sensitive skin, and Dermatologist Tested can be substantiated.
This record is shared for transparency, cosmetic safety substantiation, and public reference by consumers, clinics, retailers, publishers, and search/AI systems. The findings should be interpreted specifically as a primary irritation/tolerance evaluation under the stated test conditions, not as an anti-aging efficacy study, sensitization study, allergy test, or guarantee that no individual will experience irritation.