Mobilise-D Clinical Validation Study (CVS) dataset
Authors/Creators
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Becker, Clemens
(Project leader)1
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Miller, Ram
(Project leader)2
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Rochester, Lynn
(Project leader)3, 4
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Roubenoff, Ronenn
(Project leader)5
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Rooks, Daniel
(Project leader)2
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Maetzler, Walter
(Project leader)6
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Yarnall, Alison
(Project leader)4
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Troosters, Thierry
(Project leader)7
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Garcia Aymerich, Judith
(Project leader)8, 9
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Sharrack, Basil
(Project leader)10
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Leocani, Letizia
(Project leader)11, 12
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Vereijken, Beatrix
(Project leader)13
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Jansen, Carl-Philipp
(Project member)14
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Neatrour, Isabel
(Project member)4
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Singleton, David
(Project member)15
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Sutcliffe, Lou
(Project member)4
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Caulfield, Brian
(Project leader)15
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1.
University Hospital Heidelberg
- 2. Novartis Institutes for BioMedical Research Inc
-
3.
Newcastle upon Tyne Hospitals NHS Foundation Trust
- 4. Newcastle University
- 5. Roubenoff Consulting, LLC
-
6.
Christian-Albrechts-Universität zu Kiel
-
7.
KU Leuven
- 8. Instituto de Salud Global Barcelona
-
9.
Universitat Pompeu Fabra
-
10.
University of Sheffield
- 11. Casa di cura Igea
-
12.
Vita-Salute San Raffaele University
- 13. Norges Teknisk-Naturvitenskapelige Universitet Fakultet for medisin og helsevitenskap
-
14.
Heidelberg University
-
15.
University College Dublin
Contributors
Project leader (13):
Project member (54):
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Jansen, Carl-Philipp15
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Neatrour, Isabel4
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Singleton, David6
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Sutcliffe, Lou4
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Mikolaizak, Stefanie16
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Demeyer, Heleen17, 8
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Mazzà, Claudia11, 18
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Arnera, Valdo19
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Piraino, Paolo20
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Ammour, Nadir21
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Alcock, Lisa4
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Gaßner, Heiko22, 23
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Winkler, Jürgen24
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Klucken, Jochen25, 26
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Schlenstedt, Christian27
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Watz, Henrik28
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Kirsten, Anne-Marie29
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Chynkiamis, Nikolaos30, 31
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Vogiatzis, Ioannis32
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Hume, Emily32
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Megaritis, Dimitrios32
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Nieuwboer, Alice33
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Ginis, Pieter8
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Buckley, Ellen11, 34
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Brittain, Gavin34, 11
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comi, giancarlo35
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Helbostad, Jorunn L.36
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Johnsen, Lars Gunnar36
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Taraldsen, Kristin37
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Blain, Hubert38
- Driss, Valerie38
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Frei, Anja39
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Puhan, Milo39
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Polhemus, Ashley40
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Gimeno-Santos, Elena41
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Hopkinson, Nicholas42
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Buttery, Sara42
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Hausdorff, Jeffrey43
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Mirelman, Anat43, 44
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Evers, Jordi45
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Buekers, Joren46
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Alvarez, Paula46
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Armengol, Claudia46
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Hiden, Hugo4
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Watson, Paul47, 4
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Del Din, Silvia4
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Cereatti, Andrea48
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Mueller, Arne49
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Küderle, Arne50
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Berge, Martin A.14
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Koch, Sarah51, 52
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Delgado-Ortiz, Laura51, 52
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Josa-Culleré, Alícia
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de las Heras, Martí52
-
1.
University Hospital Heidelberg
- 2. Novartis Institutes for BioMedical Research Inc
-
3.
Newcastle upon Tyne Hospitals NHS Foundation Trust
- 4. Newcastle University
- 5. Roubenoff Consulting, LLC
-
6.
University College Dublin
-
7.
Kiel University
-
8.
KU Leuven
- 9. Instituto de Salud Global Barcelona
-
10.
Universitat Pompeu Fabra
-
11.
University of Sheffield
- 12. Casa di cura Igea
-
13.
Vita-Salute San Raffaele University
- 14. Norges Teknisk-Naturvitenskapelige Universitet Fakultet for medisin og helsevitenskap
-
15.
Heidelberg University
-
16.
Robert Bosch Hospital
- 17. Ghent University
- 18. INDIVI
- 19. Clario
- 20. Bayer AG
-
21.
Sanofi (France)
-
22.
Fraunhofer Institute for Integrated Circuits
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23.
Universitätsklinikum Erlangen
- 24. University Hospital Erlangen
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25.
University of Luxembourg
- 26. Centre Hospitalier de Lxuembourg
-
27.
MSH Medical School Hamburg – University of Applied Sciences and Medical University
- 28. Pulmonary Research Institute at LungClinic Grosshansdorf GmbH, Germany
- 29. Pulmonary Research Institute at LungClinic Grosshansdorf GmbH
-
30.
National and Kapodistrian University of Athens
-
31.
Thorax Foundation
-
32.
Northumbria University
- 33. University of Leuven
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34.
Sheffield Teaching Hospitals NHS Foundation Trust
- 35. Vita-Salute San Raffaele University, Milan, Italy
- 36. Department of Neuromedicine and Movement Science, Norwegian University of Science and Technology, Trondheim, Norway
-
37.
OsloMet – Oslo Metropolitan University
- 38. Department of Geriatrics, Montpellier University Hospital and MUSE, Montpellier, France
- 39. University of Zurich
- 40. Epidemiology, Biostatistics and Prevention Institute, University of Zurich, Zurich, Switzerland
- 41. Barcelona Institute for Global Health (ISGlobal), Barcelona, Catalonia, Spain
-
42.
Imperial College London
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43.
Tel Aviv Sourasky Medical Center
-
44.
Tel Aviv University
- 45. McRoberts BV, The Hague, Netherlands
- 46. Instituto de Salud Global de Barcelona
- 47. National Innovation Centre for Data
- 48. Politecnico di Torino
- 49. Novartis Pharma
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50.
Friedrich-Alexander-University Erlangen-Nürnberg
-
51.
University of Basel
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52.
Barcelona Institute for Global Health
Description
Mobilise-D Clinical Validation Study (CVS) Dataset
This dataset was recorded as part of the Mobilise-D project, a comprehensive initiative aimed at developing and validating digital solutions for assessing mobility in real-world environments. The Mobilise-D project seeks to address the critical need for accurate, reliable, and scalable tools to monitor and evaluate gait and mobility patterns, particularly in populations with mobility impairments.
The dataset comprises recordings from a diverse cohort of participants with various mobility-related conditions. Data collection was conducted using state-of-the-art wearable sensors and devices, capturing a wide range of gait parameters in the real world. The primary objective was to ensure the robustness and precision of digital mobility assessment tools under real-world conditions.
Key features of the dataset include:
- Demographic & Clinical Data: Age, gender, height, weight, and data from a range of clinical assessments.
- Sensor Data: Processed Digital Mobility Outcome (DMO) data from a single wearable device worn on the back, available for individual gait bouts and aggregated on a daily and weekly basis.
- Consolidated clinical and DMO data: One row per participant per visit.
- Flowcharts: A visual representation of retention and data availability.
- Data Dictionary: A reference document describing the data within the datasets provided.
Brief Overview
This dataset contains data from 2400 participants from four cohort groups that included participants with potentially altered mobility due to Parkinson's Disease (PD), Multiple Sclerosis (MS), Proximal Femoral Fracture (PFF), and Chronic Obstructive Pulmonary Disease (COPD). Participants underwent a comprehensive clinical assessment and a 7-day DMO measurement period on 5 occasions, separated by 6 monthly intervals, over 2 years. Data was recorded across multiple measurement sites and multiple countries. Data availability varies between participants, and some tests might be missing for some participants. Detailed information regarding retention and data availability is included in study flowcharts.
The Mobilise-D clinical validation study protocol is detailed in the following paper:
Mikolaizak AS, Rochester L, Maetzler W, Sharrack B, Demeyer H, Mazzà C … Jansen CP. Connecting real-world digital mobility assessment to clinical outcomes for regulatory and clinical endorsement–the Mobilise-D study protocol. PLoS ONE. 2022 Oct 6;17(10):e0269615.DOI: 10.1371/journal.pone.0269615
Tips and Notes
Data Dictionary
The Data Dictionary can be used as a reference guide defining and describing the variables published in the relevant dataset.
Flowcharts
The flowcharts outline the participant journey through the relevant visits, detailing retention and data availability for each measurement period.
General Notes
The participant IDs are "double pseudonymized" and do not correspond to data-ids used within the Mobilise-D project.
Usage Recommendation
This dataset is designed to derive insights from the patient cohorts. It may not be used for commercial purposes (see license information below).
Suggested Citation
When you are working with the data, we suggest the following citation:
Becker, C., Miller, R., Rochester, L., Roubenoff, R., Rooks, D., Maetzler, W., Yarnall, A., Troosters, T., Garcia Aymerich, J., Sharrack, B., Leocani, L., Vereijken, B., Jansen, C.-P., Neatrour, I., Singleton, D., Sutcliffe, L., & Caulfield, B. (2026). Mobilise-D Clinical Validation Study (CVS) dataset (V1.0.0) [Data set]. Zenodo. https://doi.org/10.5281/zenodo.21060991
Please cite our study protocol paper in your publications if our repository helps your research.
Mikolaizak AS, Rochester L, Maetzler W, Sharrack B, Demeyer H, Mazzà C … Jansen CP. Connecting real-world digital mobility assessment to clinical outcomes for regulatory and clinical endorsement–the Mobilise-D study protocol. PLoS ONE. 2022 Oct 6;17(10):e0269615.DOI: https://doi.org/10.1371/journal.pone.0269615
License and Legal Information
Mobilise-D Clinical Validation Study Dataset © 2026 by Mobilise-D Consortium is licensed under CC BY-NC-ND 4.0
Acknowledgments
We extend our gratitude to all participants who contributed to the Mobilise-D project, enabling the comprehensive collection and analysis of mobility data. This work would not have been possible without the dedication and collaboration of the Mobilise-D Consortium members, including researchers, clinicians, and technical staff.
We also acknowledge the funding and support provided by the European Union's Horizon 2020 research and innovation program under grant agreement No 820820. Special thanks to our partner institutions and organizations for their invaluable contributions and continued support.
Disclaimer
The Mobilise-D Clinical Validation Study Dataset is provided for research purposes only. The Mobilise-D Consortium makes no warranties, express or implied, regarding the accuracy, completeness, or reliability of the dataset. Users of the dataset assume all responsibility for any conclusions drawn from the data.
The dataset must be used in accordance with ethical guidelines and applicable laws and regulations. Any publications or presentations based on this dataset should appropriately cite the source. The Mobilise-D Consortium is not liable for any misuse of the dataset or for any direct, indirect, incidental, or consequential damages arising out of the use of the dataset.
Files
Aggregated DMO Data.zip
Files
(1.0 GB)
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