Published January 1, 2005 | Version v1

Hematologic response to four weeks of intermittent hypobaric hypoxia in highly trained athletes

  • 1. Unitat de Recerca en Farmacologia, Institut Municipal d'Investigació Mèdica, C/Doctor Aiguader 80, 08003 Barcelona, Spain
  • 2. Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, C/Doctor Aiguader 80, 08003 Barcelona, Spain
  • 3. Departament d'Hematologia, Hospital de Sant Pau, C/Sant Antoni Ma Claret 167, 08025 Barcelona, Spain
  • 4. Unitat d'Hipobària INEFC-UB, Institut Nacional d'Educació Física de Catalunya, Universitat de Barcelona, Av. de l'Estadi s/n (Anella Olímpica de Montjuïc), 08038 Barcelona, Spain

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We investigated changes induced by four weeks of intermittent hypobaric hypoxia (IHH) at a simulated altitude of 4000-5500 m in highly trained athletes. Serum erythropoietin increased significantly (p<0.001) after the sessions of IHH, but reticulocyte and red cell parameters did not. Our IHH protocol stimulated endogenous erythropoietin secretion without producing the subsequent erythropoietic response.

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Funding

Instituto de Salud Carlos III
FIS 01/1328