Raw and processed in vitro release (IVRT) data for "A modelling-based comparison of IVRT and synthetic-membrane permeation for early formulation screening"

This dataset contains the raw and processed in vitro release test (IVRT) data underlying Table 1 and Figure 1 of the article "A modelling-based comparison of IVRT and synthetic-membrane permeation for early formulation screening" (RSC Pharmaceutics, DOI: 10.1039/d6pm00035e).

Fifteen ibuprofen / poloxamer-407 gel formulations (F1–F15) were tested by IVRT on a nylon membrane over 6 h with UV–Vis quantification. The archive contains:
- 01_UV_absorbance_raw.xlsx — raw UV–Vis absorbance readings and the wavelength-derived concentrations for every sample;
- 02_UV_calibration.xlsx — ibuprofen calibration standards and wavelength-specific calibration curves;
- 03_per_formulation_processed.xlsx — per-formulation (F1–F15), per-replicate cumulative release and the means/SDs reported in Table 1;
- README.md — full file descriptions and analytical conventions.

The corresponding in vitro permeation test (IVPT) data are reported in a previous publication (Int. J. Pharm., 2025, 125306; DOI: 10.1016/j.ijpharm.2025.125306).