Published June 8, 2026 | Version v1

A CASE REPORT ON POLYCYSTIC OVARY SYNDROME WITH METABOLIC COMPLICATIONS

  • 1. Pharm.D Intern, School of Pharmaceutical Sciences, Vels Institute of Science, Technology and Advanced Studies, Pallavaram, Chennai – 600117, India.
  • 2. Assistant Professor, Department of Pharmacy Practice, School of Pharmaceutical Sciences, Vels Institute of Science, Technology and Advanced Studies, Pallavaram, Chennai – 600117, India.
  • 3. Professor and Head, Department of Pharmacy Practice, School of Pharmaceutical Sciences, Vels Institute of Science, Technology and Advanced Studies, Pallavaram, Chennai – 600117.
  • 4. Dean, School of Pharmaceutical Sciences, Vels Institute of Science, Technology and Advanced Studies, Pallavaram, Chennai, TN-600117.

Description

Background: Polycystic Ovary Syndrome (PCOS) is a rather common endocrine and metabolic disorder, mainly found in women of reproductive age. In many cases it goes together with obesity, insulin resistance, dyslipidemia and also trouble in glucose regulation, so the chance of later cardiovascular and other metabolic issues can rise over time. Case Presentation: A 26-year-old unmarried female came in with irregular menses, steady weight increase, acne, unwanted hair growth, darkening of skin in the neck folds, plus fatigue for about six months. On clinical exam there was obesity, central fat patterning, acne vulgaris, hirsutism, and acanthosis nigricans. Lab investigations suggested impaired fasting glucose, hyperinsulinemia, dyslipidemia, raised serum testosterone, and an LH:FSH ratio that was clearly increased. Pelvic ultrasonography showed bilateral polycystic ovaries with a lot of small follicles sitting around the edges. So she was diagnosed with PCOS along with metabolic syndrome, insulin resistance, dyslipidemia, obesity, and prediabetes. Treatment was not only one thing, it included lifestyle changes, metformin, hormonal management, diet guidance and regular follow-up visits. Conclusion: Early recognition of metabolic complications in PCOS is essential to prevent long-term morbidity. Multidisciplinary management and lifestyle interventions play a significant role in improving both reproductive and metabolic outcomes.

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