Published July 31, 2026 | Version v3.0.0

eidolon (formerly rusty-neat): a Rust toolkit for simulating NGS read data, including tumor/normal cancer sequencing

  • 1. National Center for Supercomputing Applications, University of Illinois Urbana-Champaign

Description

eidolon is a Rust port and extension of NEAT that generates simulated next-generation sequencing data in FASTQ and VCF formats with the statistical properties of real datasets, along with a golden BAM/VCF truth set of inserted variants and ideal alignments. It adds structural-variant simulation (CNV, BND, INV, INS, and others) and an end-to-end tumor/normal cancer workflow (gen-cancer-reads) that merges two read passes at a configurable purity and emits an origin-tagged truth VCF for benchmarking somatic and structural-variant callers, with an emphasis on low memory use and short CPU time.

Files

ncsa/eidolon-v3.0.0.zip

Files (4.1 MB)

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Additional details

Related works

Is supplement to
Software: https://github.com/ncsa/eidolon/tree/v3.0.0 (URL)

Software