Published June 5, 2026 | Version v0.1.0
Software Open

CompForce: a platform for computational cell fate engineering transcription factor prediction

Authors/Creators

  • 1. Institute for Cell Engineering and Department of Biomedical Engineering, Johns Hopkins University School of Medicine
  • 2. Department of Biomedical Engineering, Johns Hopkins University School of Medicine
  • 3. Institute for Cell Engineering, Johns Hopkins University School of Medicine

Description

CompForce (COMPutational tools FOR Cell fate Engineering) is an R platform that integrates and standardizes transcriptomic-based computational methods for predicting transcription factors that drive cell identity transitions (DESeq2, t-test, a Jensen-Shannon-divergence approach, a CellNet-style Network Influence Score, and a Mogrify-style score), and aggregates their results. Software accompanying Su, Ly & Cahan, "Prediction of parsimonious and temporally-sensitive sets of cell fate engineering transcription factors with IMCell."

Files

CahanLab/compforce-v0.1.0.zip

Files (19.0 MB)

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Additional details

Related works

Is supplement to
Software: https://github.com/CahanLab/compforce/tree/v0.1.0 (URL)

Software

Repository URL
https://github.com/CahanLab/compforce