Published June 5, 2026
| Version v1
Dataset
Open
Non-drive allele frequency dynamics in Ag(QFS)1 gene drive caged population experiments pre-seeded with R1 or R3 resistant alleles in Anopheles gambiae
Authors/Creators
-
1.
Imperial College London
Description
This dataset contains paired-read Illumina pooled amplicon sequencing data tracking non-drive allele frequencies over discrete generations in Anopheles gambiae cage population experiments with the Ag(QFS)1 gene drive, pre-seeded with known resistance alleles at the doublesex gene drive target site (an R1 G→T SNP or R3 C→T SNP).
Ag(QFS)1 heterozygous males were released at 40% (R1 cages) and 25% (R3 cages) frequency in duplicate cages pre-seeded with 15% R1 (G→T SNP) and 25% R3 (C→T SNP) resistant alleles respectively.
File naming denotes whether the sample originated from an R1 or R3 pre-seeded cage trial, the generation sampled (G0, G1, G4 or G8), the cage sampled (A, B, C or D) and the population batch sampled (1 or 2).
Cage A: population pre-seeded with R3 (replicate 1)
Cage B: population pre-seeded with R3 (replicate 2)
Cage C: population pre-seeded with R1 (replicate 1)
Cage D: population pre-seeded with R1 (replicate 2)
Files
Files
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