ASSOCIATION BETWEEN TRIGLYCERIDE–GLUCOSE (TYG) INDEX AND RISK OF METABOLIC DYSFUNCTION-ASSOCIATED FATTY LIVER DISEASE (MAFLD)

The triglyceride–glucose (TyG) index is a simple, low-cost surrogate 
marker of insulin resistance and has recently emerged as a strong predictor of 
metabolic dysfunction-associated fatty liver disease (MAFLD). MAFLD is a highly 
prevalent liver disorder closely linked with obesity, type 2 diabetes mellitus, and 
metabolic syndrome. Growing evidence suggests that elevated TyG index is 
significantly associated with the presence, severity, and progression of MAFLD. 
This review summarizes current evidence on the association between TyG index and 
MAFLD and highlights its potential role in clinical risk stratification and early 
diagnosis.