Published June 2, 2026 | Version v1
Journal article Open

ASSOCIATION BETWEEN TRIGLYCERIDE–GLUCOSE INDEX AND LIVER FIBROSIS IN ADULTS WITH METABOLISM-RELATED FATTY LIVER

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Metabolism-related fatty liver disease (MAFLD) is a highly prevalent condition strongly 
associated with insulin resistance and metabolic syndrome. Liver fibrosis is the most 
important prognostic factor determining disease progression and long-term outcomes. The 
triglyceride–glucose (TyG) index is a simple and cost-effective surrogate marker of insulin 
resistance. Recent evidence suggests that the TyG index may be associated with liver 
fibrosis severity in MAFLD patients. This study aimed to evaluate the relationship between 
TyG index and liver fibrosis stages in adults with MAFLD using biochemical markers and 
noninvasive elastography.

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