Published June 1, 2026 | Version v2
Dataset Open

Software and data for "In-silico solute transport via perivascular networks in the human intracranial space"

  • 1. ROR icon Simula Research Laboratory

Description

This repository provides the software and data for the paper 

Causemann, M., Kuchta, M., Masri, R., & Rognes, M. E. (2025). In-silico solute transport via perivascular networks in the human intracranial space.

In particular, it contains the following data:

file description
code.zip

The code used to run all simulations and postprocessing steps. Detailed instructions on how to install and run the software can be found in the following github repository:

https://github.com/MariusCausemann/brain-PVS-SAS-transport

surfaces.zip

The surface triangulations extracted from the segmentations in .ply format, suitable for viewing in e.g. paraview or further processing.

standardmesh.zip

The mesh used to run all simulations in .xdmf format.

  • standard.xdmf : complete mesh, including markers for parenchyma and CSF spaces.
  • standard_outer.xdmf : only CSF spaces.
  • *_facets.xdmf: respective boundary markers
pvsnetworks.zip

1D representation of the arterial and venous networks, as well as the 3D cylinder corresponding to the vessel diameter. 

segmentation.zip

Synthseg segmentations of the T1 data and binary masks of venous and arterial networks from Hodneland et al.

modelA.zip

Simulation results (concentration values in CSF, parenchyma and PVS) for the baseline model in the paper.

modelA.html

Interactive visualization of the tracer spreading for the baseline model in the paper. Also available here.

modelA.mp4

Animation of the tracer spreading for the baseline model in the paper.

modelA-strongVM.zip

Simulation results (concentration values in CSF, parenchyma and PVS) for the high PVS flow model in the paper.

modelA-strongVM.html

Interactive visualization of the tracer spreading for the high PVS flow model in the paper. Also available here.

modelA-strongVM.mp4

Animation of the tracer spreading for the high PVS flow model in the paper.

 

Files

code.zip

Files (16.2 GB)

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Additional details

Funding

European Commission
aCleanBrain - Brain fluids - Transport and clearance 101141807

Software