Published May 27, 2026
| Version v1
Dataset
Open
Dataset for: Inverse correlation between TP53 gene status and PD‑L1 protein levels in a melanoma cell model depends on an IRF1/SOX10 regulatory axis
Authors/Creators
-
1.
Masaryk Memorial Cancer Institute
Description
This dataset contains supplementary data associated with the publication:
Martinkova L. et al. (2024), Inverse correlation between TP53 gene status and PD-L1 protein levels in a melanoma cell model depends on an IRF1/SOX10 regulatory axis, Cellular & Molecular Biology Letters 29:117.
The dataset includes:
- RNA-seq HTSeq count matrix from TCGA Skin Cutaneous Melanoma (SKCM) samples
- Differential expression analyses comparing TP53 wild-type and TP53 hotspot mutation samples
- Supplementary tables used in the manuscript analyses
Files
Files
(828.5 MB)
| Name | Size | Download all |
|---|---|---|
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md5:f3aa7332dfdcdcff7e7e4d83a6aed735
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540.7 MB | Download |
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md5:04edbf38410796c4853ef365ab6691da
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44.1 kB | Download |
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md5:666193addf09fecc4623c341d7b8e185
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8.3 MB | Download |
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md5:dde6a4030175c4fd51217254b5917b62
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279.4 MB | Download |
Additional details
Related works
- Is referenced by
- Journal article: 10.1186/s11658-024-00637-y (DOI)
Funding
- Ministry of Education Youth and Sports
- Saving lives through research in early cancer detection and prevention: Molecular, genomic and societal factors CZ.02.01.01/00/22_008/0004644