Published May 23, 2026 | Version v1

CLINICAL AND ECHOCARDIOGRAPHIC FEATURES OF DEGENERATIVE CHANGES IN HEART VALVES AND THE VASCULAR SYSTEM IN ELDERLY PATIENTS

  • 1. Candidate of Medical Sciences, Associate Professor
  • 2. Doctor of Medical Sciences, Professor
  • 3. Doctor of Medical Sciences, Associate Professor
  • 4. Assistant
  • 5. Trainee Assistant Center for the Development of Professional Qualification of Medical Workers, Tashkent, Uzbekistan

Description

The aim of this study was to evaluate the clinical course, echocardiographic features of degenerative changes in heart valves and the vascular system in elderly patients, as well as their relationship with etiological factors. The study included 200 patients aged 60–85 years. All patients underwent clinical examination, echocardiography, and vascular ultrasound examination. Arterial hypertension was detected in 81.6%, atherosclerosis in 60.0%, dyslipidemia in 55.0%, and diabetes mellitus in 40.8% of patients. Fibrosis of the aortic valve was observed in 70.4%, calcification in 48.1%, and thickening in 55.6% of cases. The mean left ventricular ejection fraction was 51.3±6.8%. A strong positive correlation was found between aortic valve damage and the duration of etiological factors (r=+0.77). Coronary artery lesions were recorded in 56.3%, carotid artery lesions in 40.0%, and peripheral artery lesions in 22.5% of patients. The obtained results demonstrated that degenerative valvular changes and atherosclerotic vascular lesions in elderly patients have a systemic nature. Echocardiography was found to have high diagnostic value in the early detection of degenerative changes and assessment of hemodynamic disorders.

Files

83-95.pdf

Files (605.7 kB)

Name Size Download all
md5:b6a4c8e55cfe623af7b35bfe2aeb70cb
605.7 kB Preview Download

Additional details

References

  • 1.Vahanian A., Beyersdorf F., Praz F. et al. 2021 ESC/EACTS Guidelines for the management of valvular heart disease // European Heart Journal. – 2022. – Vol. 43(7). – P. 561–632.
  • 2.Otto C.M., Nishimura R.A., Bonow R.O. et al. 2020 ACC/AHA Guideline for the Management of Patients With Valvular Heart Disease // Circulation. – 2021. – Vol. 143(5). – e72–e227.
  • 3.Baumgartner H., Hung J., Bermejo J. et al. Echocardiographic assessment of valve stenosis: EACVI recommendations // European Heart Journal Cardiovascular Imaging. – 2017. – Vol. 18(3). – P. 254–275.
  • 4.Lindman B.R., Clavel M.A., Mathieu P. et al. Calcific aortic stenosis // Nature Reviews Disease Primers. – 2016. – Vol. 2. – P. 16006.
  • 5.Pibarot P., Dumesnil J.G. Improving assessment of aortic stenosis // Journal of the American College of Cardiology. – 2012. – Vol. 60(3). – P. 169–180.