Published May 23, 2026 | Version v2.0.5
Software Open

bancpipeline: Data pre-processing pipeline for the BANC connectome

Authors/Creators

  • 1. Harvard Medical School
  • 2. Princeton Neuroscience Institute
  • 3. Yikes LLC
  • 4. Boston Children's Hospital, Harvard Medical School

Description

Post-proofreading pipeline for the Brain And Nerve Cord (BANC) connectome (Bates, Phelps, Kim, Yang et al., 2025). Produces the analysis-ready data files released alongside the paper: skeletonization, cross-dataset neuron matching (NBLAST + connectivity), axon-dendrite splitting, neuropil assignment to synapses, neurotransmitter and metric enrichment, and consolidated per-neuron metadata. Headline algorithmic contribution: annealed morphology + connectivity cell-type alignment, paper Methods §'Automated typing by morphology and connectivity'.

Files

htem/bancpipeline-v2.0.5.zip

Files (1.6 MB)

Name Size Download all
md5:870301ed3cf103f781b042d6c07a1fce
1.6 MB Preview Download

Additional details

Related works

Is source of
Dataset: 10.7910/DVN/7WTH1N (DOI)
Is supplement to
Preprint: 10.1101/2025.07.31.667571 (DOI)

Funding

Wellcome Trust
A neural Cartesian coordinate system for generating flexible internal goals 222782
National Institutes of Health
Investigating descending control of walking 1K99NS129759-01
National Institutes of Health
Structural variation in neuronal circuits as a basis for functional and behavioral individuality 1R01NS121874-01
National Institutes of Health
Tools to broaden access to high-throughput functional connectomics 1RF1MH117808-01A1

Software

Repository URL
https://github.com/htem/bancpipeline