Published June 5, 2026
| Version 1.0.0.
Dataset
Open
Benchmarks and results for article "Aptamers without SELEX: de novo design from protein structure in hours"
Authors/Creators
-
Dolgusheva, Vladislava
(Researcher)1
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Kudryashova, Nataliya
(Project manager)1
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Mukanov, Artem
(Researcher)1
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Kuznetsov, Ivan
(Researcher)1
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Leibin, Iosif
(Researcher)1
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Manasyan, Artem
(Researcher)1
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Pavlyuk, Gleb
(Researcher)1
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Mishkorez, Ivan
(Researcher)1
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Keremet, Anna
(Researcher)1
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Podlesnyi, Pavel
(Researcher)1
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Kalinkin, Aleksey
(Researcher)1
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Avdeev, Kirill
(Researcher)2
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Kuznetsov, Maxim
(Researcher)2
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Parfenov, Nikita
(Other)1
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Gromov, Stanislav
(Related person)1
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Ufaev, Dmitry
(Sponsor)1
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Nasaev, Shamsudin
(Work package leader)1
- 1. Xelari, Inc
- 2. Mad Devs, LLC
Description
This deposit contains the validation and test datasets supporting the manuscript "Aptamers without SELEX: de novo design from protein structure in hours" (Xelari, Inc.). The data accompany the Xelari computational pipeline for de novo DNA and RNA aptamer design from protein 3D structure.
Contents
xelari-valid-2026.zip- validation data and results for AliNA, DiNA, Edgar, Ehrlich, ValentiNA modules.
Experimental binding affinities for the three Treponema pallidum aptamers (Tpp17, Tpp47, Tp0751) designed end-to-end by the pipeline are reported in the companion wet-lab study (Bruno et al., J. Fluoresc. 2026, DOI: 10.1007/s10895-026-04717-4).
Funded by Xelari, Inc. No external funding.
Files
Xelari-valid-2026.zip
Additional details
Related works
- References
- Publication: 10.1007/s10895-026-04717-4 (DOI)
- Software: https://github.com/XELARI-CORP/naskit (URL)
- Software: https://github.com/XELARI-CORP/AliNA (URL)
- Software: https://github.com/XELARI-CORP/Edgar (URL)
Dates
- Submitted
-
2026-05-30
References
- 10.1007/s10895-026-04717-4
- https://github.com/XELARI-CORP/AliNA
- https://github.com/XELARI-CORP/Edgar
- https://github.com/XELARI-CORP/naskit