mOTUs marker gene database (v4)

Note: This is version 4.1 of the mOTUs marker gene database. It directly relates version 4.1 of the mOTUs genome database.

Changes:

• The clustering, the mOTUs, the MGCs and MGs are unchanged from 4.0 to 4.1
• ~150k MAGs from extreme environments were added. Those MAGs were associated with existing mOTUs where possible or assigned to the no_mOTU group
• Access to the functional annotation of the 150K MAGs added to the motus genomes routine
• Updated GTDB taxonomy from R220 to R226 for all genomes in the mOTUs database

Database for the marker gene-based OTU (mOTU) tool (v4). The mOTUs profiler is a computational tool that estimates relative abundance of known and unknown microbial community members using metagenomic shotgun sequencing data.

Github directory of the tool: link

In the current version, 124,295 species-level taxonomic units (mOTUs) were constructed using sequences of 10 single-copy marker genes recovered from mOTUs-db, a collection of 2.83 million metagenome-assembled genomes (MAGs) and 919 090 single-cell and isolate genomes. 30,256 mOTUs are represented by an isolate genome, whereas 94,039 mOTUs are represented by MAGs only. The source genome database is accessible at https://motus-db.org/.