ClinicalVerifier: A Retrieval-Augmented Pipeline for Detecting Guideline Contradictions in LLM-Generated Mental Health Text
Contributors
Researcher:
Description
Large language models (LLMs) are increasingly deployed in mental health applications, yet their outputs may silently contradict clinical guidelines, posing serious patient safety risks. This paper presents ClinicalVerifier, a retrieval-augmented generation (RAG) system that automatically detects when LLM-generated clinical text contradicts NICE and WHO evidence-based guidelines.
The system combines a FAISS-indexed embedding store of guideline excerpts with an LLM judge (Llama-3.3-70B via Groq), augmented by a Neighbourhood Consistency Scoring (NCS) hallucination probe to produce calibrated combined risk levels (LOW / MEDIUM / HIGH). Guideline sources include NICE CG90, NG185, CG178, NG116, CG53, CG42, and the WHO mhGAP Intervention Guide 2023.
Evaluated on a 30-case labelled benchmark spanning safe, uncertain, and contradicts clinical outputs, ClinicalVerifier achieves:
- 73.3% overall accuracy
- 95.2% F1 on safety-critical contradiction detection
- 100% recall on guideline-contradicting cases
- 100% precision on HIGH combined-risk alerts
The system's conservative design ensures no guideline violations are missed, while the dual-signal architecture (RAG verdict + NCS score) minimises false alarms. The pipeline is fully open-source, runs without proprietary API access, and is designed for integration into clinical AI monitoring workflows as a sidecar service.
Files
ClinicalVerifier_preprint.pdf
Files
(36.1 kB)
| Name | Size | Download all |
|---|---|---|
|
md5:3823217310e93243fd79fa6cf85e9958
|
36.1 kB | Preview Download |
Additional details
Software
- Repository URL
- https://github.com/thomayuri-ma/clinical-verifier