SwiftTCR

Description

Table of contents (En)

• AF3_SwiftTCR
  Results obtained from running either:

  • AlphaFold 3 (AF3) alone, or
  • SwiftTCR: Using SwiftTCR to model TCRpMHC using multiple AF3-generated TCR conformations together with pMHC structures modeled with PANDORA.
• benchmark38set: 
  SwiftTCR benchmark results on the 38 pMHC-I benchmark set
  Benchmark dataset from Peacock & Chain (2021).
  • SwiftTCR_single
    SwiftTCR predictions using a single TCR conformation and a single pMHC conformation as input.
    Unbound experimental X-ray structures of both the TCR and pMHC were used.
  • SwiftTCR_ensemble
    SwiftTCR predictions using multiple AF3-generated TCR conformations together with unbound experimental X-ray pMHC structures as input.
  • A part is in another Zenodo:
SwiftTCR_ensemble_3_swifttcr_output
https://doi.org/10.5281/zenodo.20083389
• docking_angle_statistics
  Crossing angles and incident angles calculated from 177 experimental TCR–pMHC-I structures available in the IMGT/PDB database (retrieved on 06/06/2023).
  The angle statistics were obtained from TCR3d as described by Lin et al. (2025).