Published April 30, 2026 | Version 1.1
Dataset Open

Single-nucleus RNA sequencing of human post-mortem brain tissue from Parkinson's disease and control donors

Description

This Zenodo deposit contains a publicly available description of the Dataset:

Title: "Single-nucleus RNA sequencing of human post-mortem brain tissue from Parkinson's disease and control donors".

Description: Single RNA-seq data from 128 samples derived from PMDBS samples across Inferior Parietal Lobule (IPL), and Anterior Cingulate Cortex (ACG). Types of Samples: Late stage (Braak 5-6) PD and control post-mortem brains.

This dataset is made available to researchers via the ASAP CRN Cloud: cloud.parkinsonsroadmap.org. Instructions for how to request access can be found in the User Manual.

This research was funded by the Aligning Science Across Parkinson's Collaborative Research Network (ASAP CRN), through the Michael J. Fox Foundation for Parkinson's Research (MJFF).

This Zenodo deposit was created by the ASAP CRN Cloud staff on behalf of the dataset authors. It provides a citable reference for a CRN Cloud Dataset

Version bump from 1.0 to 1.1 The updated Datasets fix inconsistencies in the ASAP assigned `ASAP_subject_id` and `ASAP_sample_id` for these previously released PMDBS Datasets. These erroneously included the string "PMBDS", now replaced with "PMDBS". This change does not affect the underlying data files, but does update the metadata to be consistent with the naming convention used for all other PMDBS Datasets and the corresponding CDEs.

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Additional details

Funding

Aligning Science Across Parkinson's
Dissecting the mechanisms underlying disease progression in parkinsonism ASAP-000478

References