Published April 29, 2026 | Version SpaceTracer v2.0.0
Software documentation Open

Detection of Somatic Point Mutations Directly from Spatial Transcriptomics Enables in vivo Spatiotemporal Lineage Tracing

Authors/Creators

Description

SpaceTracer Resource Package

This archive contains pre-built genome reference resources required to run SpaceTracer, a computational tool for precise detection of genomic mosaic single-nucleotide variants (SNVs) directly from spatial transcriptomics and related data types.

Repository: douymLab/SpaceTracer
Version: v2.0.0

File Contents

The resources.tar archive contains two compressed genome reference packages:

File Description
mm10_resources.tar.zst Mouse reference resources (mm10 / GRCm38)
hg38_resources.tar.zst Human reference resources (hg38 / GRCh38)

Extraction Instructions

# Extract the main archive
tar -xf resources.tar

# Extract mouse genome resources (mm10)
mkdir -p mm10 && zstd -d mm10_resources.tar.zst | tar -xf - -C mm10

# Extract human genome resources (hg38)
mkdir -p hg38 && zstd -d hg38_resources.tar.zst | tar -xf - -C hg38

Demo Input Files

The demo_input.tar archive contains example input files for running SpaceTracer.

Note: Example configuration files are available under SpaceTracer/config/ in the GitHub repository.

Extract demo files

tar -xf demo_input.tar

Directory structure

demo_input/
├── human_demo.bam
├── human_demo.bam.bai
├── human_demo.cell_number.txt
├── human_demo.cluster.txt
├── human_demo.tissue_positions_list.csv
├── mouse_demo.bam
├── mouse_demo.bam.bai
├── mouse_demo.cell_number.txt
├── mouse_demo.cluster.txt
└── mouse_demo.tissue_positions_list.csv

Files

Files (7.0 GB)

Name Size Download all
md5:3708093866b369133e26ade889836538
7.3 MB Download
md5:96884402299fb80af4ff12d7c947237f
7.0 GB Download

Additional details

Identifiers

DOI
10.64898/2026.02.04.703493

Related works

Is documented by
Publication: 10.64898/2026.02.04.703493 (DOI)

Dates

Created
2026-04-29

Software

Repository URL
https://github.com/douymLab/SpaceTracer