Published April 28, 2026 | Version v1
Software Open

OS-CMR Analysis: Cycle-Specific Oxygenation-Sensitive Cardiac MRI Analysis Pipeline

Description

Python pipeline for cycle-specific biomarker extraction from oxygenation-sensitive cardiac MRI acquired during vasoactive breathing maneuvers (hyperventilation and breath-hold). Computes percent-change biomarkers (HVMORE, BH-MORE) of myocardial mean intensity, heterogeneity, and entropy across the cardiac cycle, then integrates them over user-defined phase windows to produce summary measures (pAUC, pVar). Includes a command-line interface, Streamlit browser UI for non-technical users, and a synthetic data generator for testing. This release reproduces values published by the authors bit-exactly across a 68-subject test cohort.

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oscmr-analysis-v1.0.0.zip

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Additional details

Related works

Is supplement to
Journal article: 10.1093/ehjci/jeaf367.372 (DOI)