Quantifying Structural Attrition via the Mechanical Aging Index (R_age): The Axis 0 Framework V2.0.

Axis 0 Framework: R_age (Version 2.0)

This version redefines biological aging as Instantaneous Mechanical Attrition rather than a linear time-based process. It introduces the Mechanical Aging Index (R_age) to quantify structural wear at the nuclear level.

Key updates in V2.0:

• Variable t: Redefined as the instantaneous force variation axis.
• R_age Equation: A mathematical model to predict genomic "Lock-in" and Lamin fatigue.
  Inverse Pressure Strategy: A specialized protocol for mechanical intervention based on tissue mechanosensitivity (K-coefficient).

The record includes:

1. Comprehensive Technical Report: Theoretical foundations and biophysical mechanisms.
2. Operational Protocol (SOP): Practical guidelines for Axis 0 machine implementation.