All metadata and supplementary tables for NYGC ALS Consortium

All metadata and supplementary tables for the NYGC ALS Consortium flagship resource paper.

NYGC_Flagship_ST_1_3_Metadata.xlsx

Data dictionary - including column definitions

Member list - all NYGC ALS Consortium member sites

ST1: all WGS and donor-level clinical metadata

ST2: WGS mutation annotations

ALS gene list - all ALS genes used for annotations

ST3: all RNA-seq metadata

NYGC_Flagship_ST_4_16_expression.xlsx

ST4: all case-control DEGs across tissues

ST5: all GSEA GO analysis merged, with column for comparison and tissue

ST6: all GO enrichment for tissue intersections

ST7: all deconvolution estimates across all tissues and cell-types

ST8: all deconvolution statistics, across all tissues and cell-types

ST9: cell-type marker GSEA results

ST11-15: clinical DEGs

ST16: clinical GO/KEGG enrichment on age death and duration

NYGC_Flagship_ST_17_31_splicing.xlsx

ST17-22: Categorical Case-control, C9, limb-bulbar DS results at FDR < 0.05, long format, clusters and intron

ST23-28: Continuous DS results, onset, death, duration (clusters and introns)

ST29-31: DS enrichments

NYGC_Flagship_ST_32_35_genetics.xlsx

ST32: QTL discovery

ST33: QTL sharing

ST34: COLOC results 

ST35: STR-QTL results