Published April 28, 2026 | Version v1
Preprint Open

Gymnema sylvestre Extract for Alternative Glucose Metabolism Pathway Activation

Authors/Creators

  • 1. MedicOath

Description

Gymnemic acids in Gymnema sylvestre activate FOXO1-mediated gluconeogenesis through G6PC and PCK1 upregulation while enhancing glycogen synthesis via GSK3β inhibition, providing glucose-based energy production to compensate for impaired fatty acid β-oxidation in MCADD patients

Notes

IPFS: QmTwMPakLD5wsevu9ypnayjCmTz1zdnzZBpA8ag1E2fanD. TX: 0x4220e5a0f2a3e755ec1b2e2bd329f779518595030ebc43cb47583c768a613c67. CC0.

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