Published April 28, 2026 | Version v1
Preprint Open

Microbiome-Derived Indole-3-Lactic Acid for Aryl-Hydrocarbon Receptor Activation

Authors/Creators

  • 1. MedicOath

Description

Gut microbiota produce indole-3-lactic acid which activates aryl-hydrocarbon receptors, reducing amyloidopathy through neuroinflammation modulation. Faecalibacterium prausnitzii strains show specific benefits for Alzheimer's pathology. This represents a microbiome-brain axis intervention targeting both peripheral inflammation and central amyloid pathology.

Notes

IPFS: QmPQ4eVzG8oEx8cjKh8VWczjZsnjnbCnus1b8ZAjY5ZFAK. TX: 0x99ef5eff5baad13e3c50221830bd1f0005c5118f7063aa6a53529a56a795451d. CC0.

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