Published April 28, 2026 | Version v1
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Glymphatic System Enhancement via Baicalein-Induced AQP4 Polarization and Perivascular Clearance

Authors/Creators

  • 1. MedicOath

Description

Baicalein restores proper AQP4 polarization in astrocytic endfeet through modulation of dystrophin-dystroglycan complex and α-syntrophin interactions. Enhanced AQP4 polarization improves glymphatic flow and perivascular clearance of protein aggregates, reducing neuroinflammation via NF-κB pathway inhibition.

Notes

IPFS: QmUitRguUudqmWnRcwYt1PgxDqZCq9oujZCjJi4ZmjxyBM. TX: 0x0a30f2dc28a7b2d5e7010a9cd3e782f120dad8885497e2b4588919a2a1d4385e. CC0.

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