Published April 28, 2026 | Version v1
Preprint Open

Recombinant Herpes Zoster Vaccine for Dementia Prevention via Neuroinflammation Reduction

  • 1. MedicOath

Description

NCT07485283 is testing Shingrix vaccine for dementia prevention in Phase 4. Herpes zoster reactivation causes neuroinflammation through microglial activation. Preventing reactivation with vaccination could reduce chronic neuroinflammation, a key driver of multiple dementia types.

Notes

IPFS: QmfA3yHexyUha2gLrbNWBsFK7A6fYYWTTi9C1WSjsRqdsm. TX: 0x969f365cf3d3a3dad3b6801a002783802b51ecd0fdb81112699efe9df0ee2589. CC0.

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