Published April 28, 2026 | Version v1
Preprint Open

Omega-3 Fatty Acids Combined with BCL11A Modulation

  • 1. MedicOath

Description

Clinical trial NCT07530965 is testing flaxseed omega-3 fatty acids in SCD children. BCL11A (transcription factor, UniProt Q9H165) has 0.47 association score with SCD (Open Targets) and regulates fetal hemoglobin. Omega-3s may enhance BCL11A-targeted therapies by reducing inflammation via cytokine-cytokine receptor interactions (KEGG hsa04060, linked to HBB).

Notes

IPFS: QmanfYXict5Gvj8FHTGQau9uXpuMppb8Ddd6RYyRL4Q8oZ. TX: 0x468cdca8d4f3992376f43c4321f383d0fe9b87c2387a166289ed45006ffe01c0. CC0.

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