Published April 28, 2026 | Version v1
Preprint Open

TRIAC combination with selective THRB agonists for preferential brain targeting

Authors/Creators

  • 1. MedicOath

Description

Combining TRIAC (3,3',5-triiodothyroacetic acid) with novel selective THRB agonists like VK2809 to achieve optimal thyroid hormone receptor activation in brain while minimizing peripheral hyperthyroidism through tissue-selective receptor subtype targeting

Notes

IPFS: QmT1MRN6mrHg3qqAky5fm4SJwzyaP1PktW1JbanhqEuxhK. TX: 0xd141019c3d03f404047927dad428d683c71e1fb01d7d8d52b6f6ab262ec7b513. CC0.

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