Phytochemical Profiling and Antibacterial Evaluation of Polianthes tuberosa L. (Flowers, Stems, and Tubers) Against Acne-Associated Bacteria

Germs such as Staphylococcus aureus and Cutibacterium acnes are often the causes of the skin disease called acnes vulgaris. The need to find alternative plant-based compounds that could hopefully replace standard antibiotics has increased the pace of search given the increased resistance to these compounds. In the present study, polianthes tuberosa L. extracts of flower, stems, and tubers were examined based on the phytochemical composition and anti-bacterial properties. Solvents extracts were prepared using the traditional methods of extracting solvents, and were initially subjected to phytochemical analysis. Agar well diffusion method was used to assess the antibacterial activity against acnes causing microorganisms and minimum effective concentration of the most active extract was calculated. The results showed that all of the plant components that were examined had antibacterial activity. The flower extracts had the largest zone of inhibition which extended to the tuber extracts and then stem extracts. Phytochemical analysis revealed the presence of bioactive constituents (glycosides, tannins, alkaloids, saponins, and flavonoid, etc.). The antibacterial effect identified could be due to the interaction of these phytoconstituents. These findings support the hypothesis that Polianthes tuberosa L. could be utilized in the development of herbal remedies to fight acnes due to its antibacterial effects and that it can be used to attack the microorganisms that cause the condition. Further studies ought to concentrate on isolating bioactive compounds and authorising their effects to living organisms.