Published May 21, 2026 | Version v5

D3-DNA: Data and Model Weights for DNA Discrete Diffusion

  • 1. Cold Spring Harbor Laboratory

Description

Data files and pretrained model weights for D3: DNA Discrete Diffusion, a discrete diffusion framework for conditional generation of DNA regulatory sequences.

V2 additions: Adds D3_Conv_DeepSTARR.pth and D3_Conv_MPRA_HepG2.pth (SEDD-format convolutional backbones; d3_dna.io.load_checkpoint handles both .ckpt and .pth). README updated.

V4 additions: Adds Oracle_promoter.sei.names feature mask necessary to run inference with Oracle_Promoter.pth.tar README updated.

V5 additions: Adds the tabulated sequence + RNA/DNA counts for the wet lab validation assays.

 

Package: https://github.com/anirbansarkar-cs/d3-dna

Research code: https://github.com/anirbansarkar-cs/D3-DNA-Discrete-Diffusion

Files

d3_wet_lab_validation_results.csv

Files (17.0 GB)

Name Size
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