Multi-Site Validation Across the United States: Real-World Testing of a Portable Microplastic/Nanoplastic Water Assay

The EcoExposure™ portable optical assay was evaluated across five geographically and hydrogeologically distinct U.S. locations: Cincinnati (OH), Milwaukee (WI), St. Louis (MO), Denver (CO), and San Francisco (CA). These sites represent a wide range of source-water types, municipal treatment systems, climates, elevations, and ionic compositions. In addition, separate validation was conducted in San Francisco Bay coastal saltwater. The assay produced clear, interpretable optical signatures in all tap-water and environmental freshwater matrices tested, demonstrating robustness across real-world conditions. These results provide strong empirical support for the platform’s suitability for distributed, decentralized deployment anywhere in the United States.