Published April 20, 2026 | Version v1
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ATYPICAL MANIFESTATIONOF CUTANEOUS INFANTILE HEMANGIOMAS: TWO RARE CASE REPORTS

  • 1. 1. Professor and Head of Dermatology Department Naimat Begum/Hamdard University Hospital, Karachi.
  • 2. 2. MBBS, Hamdard University, Karachi.
  • 3. 3. Consultant Paediatrician at WWL NHS Trust Hospital, UK.

Description

Background: Infantile hemangioma (IH), or strawberry naevus, is a benign, bright-red vascular birthmark caused by rapid blood vessel growth, affecting 4-10% of infants. It usually involves the head and neck, rarely the limbs and genitalia, grows rapidly for 12–15 months, and then gradually regresses over years. Treatment includes topical beta-blockers and steroids, oral corticosteroids and beta blockers, laser therapy, or surgical options in certain cases. In this case report, we included atypical presentations of IH in infants. The aim of study: To assess atypical presentations, changes in size, morphology, progression and treatment response in varieties of hemangioma. Case Reports: We presented two cases with rare and uncommon, atypical presentations of IH who came to NBH/HUH, Karachi. Case 1 involved a3-month-old female with a typical presentation characterized by a solitary, asymmetric rapidly enlarging vascular lesion on right deltoid region, treated with 2% topical propranolol and oral steroids resulting in regression with color changes and atrophy of the lesion over a period of one year. Case 2 involved a 3-month-old male with an atypical presentation characterized by multiple, bilateral symmetrical lesions (atypical manifestation) on extensor surfaces of both wrists and the penile area, treated with 2% propranolol but patient was lost to follow up.

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