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This study develops and validates a comprehensive management model for efficient utilization of natural-economic resources in the Kashkadarya region of Uzbekistan. The research analyzes resource management practices across five key districts of the region over the 2020–2023 period, examining agricultural land, mineral resources, and water resource management systems. Using a multi-criteria evaluation framework combining GIS spatial analysis, stakeholder surveys (n=180), and institutional performance assessment, the study identifies significant variation in management effectiveness across districts and resource categories. The proposed Regional Resource Management Model integrates strategic planning, operational monitoring, stakeholder coordination, and performance evaluation components, demonstrating effectiveness improvements of 68–84% in pilot implementation sites. The research contributes region-specific management tools adaptable to comparable resource-rich regions of Central Asia.
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