ViroDyn Ulcerative Colitis GWAS Atlas v1.0.0

This Zenodo record contains ViroDyn Ulcerative Colitis GWAS Atlas v1.0.0, a versioned, machine-readable atlas of ulcerative colitis genetics centred on the GWAS Catalog trait ulcerative colitis (EFO_0000729).

The release integrates live GWAS Catalog study enumeration with GWAS Catalog top hits, alongside a comprehensive suite of downstream resources. These include a machine-readable summary statistics manifest, mirrored redistributable harmonised summary statistics, locus definitions, credible sets, variant consequence and variant-to-gene mapping, gene prioritisation scores, pathway and network context, therapeutic target overlays, controlled-access manifests, quality control reports, checksums, and a query-ready DuckDB bundle.

Version 1.0.0 contains:

• 184 study registry rows
• 2,282 top-hit rows
• 67 summary statistics manifest rows
• 53 mirrored harmonised study partitions comprising 793,314,938 harmonised association rows
• 2,621 loci
• 5,614 credible set rows
• 1,446 variants
• 37,398 variant-to-gene mapping rows
• 3,493 gene score rows

The canonical release build is GRCh38, with GRCh37 compatibility retained where available.

Controlled-access resources are represented as manifests rather than redistributed data. Linked external assets, including Pan-UK Biobank and FinnGen, remain explicit external references within the release metadata.

This record is designed to support reproducible ulcerative colitis GWAS discovery, locus follow-up, replication review, variant-to-gene interpretation, target prioritisation, and AI-assisted downstream analysis.

Users should cite this atlas alongside the GWAS Catalog, Open Targets, and the original study publications when making study-specific or biological claims.