Surgery
Published March 30, 2026 | Version v1
Journal article Open

Survival and prognostic factors in the surgical treatment of mediastinitis – a single-center clinical study

Authors/Creators

  • 1. University Hospital "St. Ekaterina" - Sofia
  • 2. University Hospital "Alexandrovska"- Sofia

Description

Mediastinitis is a severe and potentially life-threatening condition with high mortality, in which surgical treatment plays a key role in disease outcome. The present single-center clinical study aims to evaluate survival and identify prognostic factors among patients with surgically treated mediastinitis. Lower survival was associated with higher inflammatory markers, whereas more aggressive surgical methods were associated with better clinical outcomes. These findings highlight the importance of timely diagnosis and an individualized therapeutic approach to improve survival in patients with mediastinitis.

Abstract (Bulgarian)

Медиастинитът е тежко и потенциално животозастрашаващо състояние с висока смъртност, при което хирургичното лечение играе ключова роля за изхода от заболяването. Настоящото едноцентрово клинично проучване има за цел да оцени преживяемостта и да идентифицира прогностичните фактори при пациенти с медиастинит, лекувани хирургично. Установено е, че по–ниската преживяемост е свързана с по–високи маркери на възпаление, а по–агресивните хирургични методи се асоциират с по–добри клинични резултати. Това подчертава значението на навременната диагноза и индивидуализирания терапевтичен подход за подобряване на преживяемостта при пациенти с медиастинит.

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Additional details

Additional titles

Translated title (Bulgarian)
Преживяемост и прогностични фактори при хирургично лечение на медиастинит – едноцентрово клинично проучване

Identifiers

ISSN
3033-151X
URL
https://bgss.eu/index.php/surgery/article/view/78

Dates

Issued
2026-03-30

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