Published April 13, 2026 | Version v1

PHARMACOLOGICAL MECHANISMS OF DRUG ACTION: PRINCIPLES AND APPLICATIONS

  • 1. Termez University of Economics and Service, Faculty of Medicine

Description

Pharmacology is a fundamental discipline in medical science that studies the interactions between drugs and biological systems. This article explores the core principles of pharmacological mechanisms, including pharmacokinetics and pharmacodynamics. Special emphasis is placed on how drugs are absorbed, distributed, metabolized, and excreted, as well as their effects at the cellular and receptor levels. Understanding these mechanisms is essential for rational drug use, minimizing adverse effects, and optimizing therapeutic outcomes. This paper follows the IMRAD structure to provide a comprehensive scientific overview.

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References

  • 1. Goodman & Gilman (2018). The Pharmacological Basis of Therapeutics. McGraw-Hill. (Indexed in PubMed, Scopus) 2. Rang, H. P., et al. (2019). Rang & Dale's Pharmacology. Elsevier. 3. Katzung, B. G. (2021). Basic & Clinical Pharmacology. McGraw-Hill. 4. World Health Organization (2020). Guidelines on Rational Use of Medicines. 5. Brunton, L. L. (2018). Drug metabolism and pharmacokinetics. Journal of Pharmacology.