Published April 9, 2026
| Version v1
Dataset
Open
Shared genetics of blood traits identify clonal hematopoiesis risk loci and a polygenic predictor of leukemia risk
Authors/Creators
- 1. University of Bristol, MRC Integrative Epidemiology Unit
- 2. Imperial College London, School of Public Health
Description
Each data set contains the following four columns:
SNP = single nucleotide polymorphism rsID
CHR = chrosmome number
BP = base pair position in build 37 of the human genome
FP = the functional P-value (interpreted like a standard P-value) from the surrogate functional False Discovery Rate (sfFDR) analysis of the UK Biobank genome-wide association summary statistics from Kessler, et al. (https://doi.org/10.1038/s41586-022-05448-9).
The overall_inc_ch_bcx_eur_sffdr_res.txt file contains results for the overall clonal hematopoiesis (CH) phenotype. The overall_exc_ch_bcx_eur_sffdr_res.txt file contains results for the overall CH phenotype after excluding individuals carrying mosaic chromosomal alterations.
Files
asxl1_ch_bcx_eur_sffdr_res.txt
Files
(1.9 GB)
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