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Published April 8, 2026 | Version v1

D3-DNA: Data and Model Weights for DNA Discrete Diffusion

Authors/Creators

  • 1. Cold Spring Harbor Laboratory

Description

Data files and pretrained model weights for D3: DNA Discrete Diffusion, a discrete diffusion framework for conditional generation of DNA regulatory sequences.

Code: https://github.com/anirbansarkar-cs/D3-DNA-Discrete-Diffusion
Package: d3-dna (pip install d3-dna)

This deposit contains LentiMPRA datasets (K562, HepG2, WTC11), LegNet oracle checkpoints for evaluation, a DeepSTARR oracle, and the D3-Transformer diffusion model trained on K562. Additional datasets and model weights will be added in future versions.

Files

README.md

Files (4.1 GB)

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Additional details