Analysis of Role of Haematological Parameters in diagnosis of Urinary Tract Infection in a Tertiary Care Centre: A Case Control Study

Background: UTI is one of the common bacterial infections and may lead to serious morbidity and mortality. In the present study, a systematic evaluation of haematological parameters was done to analyse the role of these markers in early diagnosis of UTI. These findings were further compared with the microbiological culture results to demonstrate a link between the haematological indices and the type of organism, whether gram positive or gram negative to allow proper selection of the empiric antibiotic regimen.

Objective: To evaluate the diagnostic significance of haematological parameters   in the diagnosis of urinary tract infection in a tertiary care centre .

Materials and Methods: A prospective case-control study was conducted at Srinivas Hospital, Srinivas Institute of Medical Sciences and Research Centre(tertiary care centre), Mukka from September 2025 to February 2026.The study analysed haematological data from 145 culture-confirmed UTI cases and compared it with 145 culture-negative non UTI controls. Haematological parameters such as Haemoglobin, WBC count, Platelet count, MPV,RDW and PDW were analysed using an automated haematology analyser. Urine culture results were correlated with above haematological parameters.

Results: The UTI patients exhibited lower Hb and higher WBC, platelet count, MPV, RDW and PDW compared to controls. Gram-positive UTI infections showed higher WBC count, platelet counts, RDW and PDW , but lower MPV compared to gram-negative UTI infections.

Conclusion: Haematological parameters could serve as potential biomarkers in diagnosis of UTI’s. It was also useful in differentiating gram positive and gram negative UTI’s.