Published April 2, 2026 | Version v1
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A DIAGNOSTIC ODYSSEY: NON-HODGKIN LYMPHOMA MASQUERADING AS RECURRENT TYPHOID FEVER AND NEPHROLITHIASIS - A 14-MONTH DELAY IN DIAGNOSIS AND COMPREHENSIVE TREATMENT OUTCOME

  • 1. 1. Associate Professor, Smt. Sumitrabai Thakare College of Nursing, Yavatmal.

Description

Background: Diagnostic delay in haematological malignancy remains a significant clinical problem, particularly when concurrent endemic infections and benign structural pathology provide plausible alternative explanations for constitutional symptoms. Non-Hodgkin Lymphoma presenting alongside confirmed typhoid fever and nephrolithiasis poses an exceptionally challenging diagnostic scenario. Objective: To document the clinical, diagnostic, and treatment journey of a 38-year-old male patient with Stage IIIB Diffuse Large B-Cell Lymphoma (DLBCL) whose diagnosis was delayed by 14 months due to concurrent Salmonella typhi infections and bilateral nephrolithiasis, and to describe the complete treatment response to dose-dense R-CHOP-15 followed by Rituximab maintenance.

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