Research Article On Analytical Method Development And Validation Of Rivastigmine In Pure Form By Using Uv- Visible Spectroscopy

For the determination of rivastigmine in pure dose form, a straightforward, specific, accurate, and exact UV spectrophotometric approach was created and verified. Weighing 100 mg of standard Rivastigmine in 1000 ml of 1N HNO3 in a volumetric flask yielded the stock solution. Using 1N HNO3, the final stock solution was created to yield 1g/µl. Additional dilutions were made in accordance with protocol and scanned at 245 nm. The concentration range of 1–5 µg/ml was where the linearity was discovered. 0.998 was the correlation coefficient. The regression equation for the pure form of rivastigmine was determined to be Y = 0.0057x + 0.3068.Recovery of Rivastigmine was found to be in the range of 98-102%. The method was validated for limit of detection limit of quantification for estimation of Rivastigmine was found to be µg/ml and µg/ml respectively. The Proposed method can be successfully applied for the quantitative determination of Rivastigmine in pure form.