Published March 30, 2026 | Version v1
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Long COVID: Manifestaciones Neurológicas

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Research Paper: Long COVID: Manifestaciones Neurológicas. Abstract/Summary: ARTICLE Long COVID Neurological and Psychiatric Symptoms: A Systematic Review of Global Prevalence Data (2021-2024) and Clinical Implications Juan Moisés de la Serna 1,* 1 , Logroño, Spain; juanmoises.delaserna@.net * Correspondence: juanmoises.delaserna@.net; ORCID: 0000-0002-8401-8018 Abstract: Post-COVID-19 condition (PASC), commonly known as Long COVID, is characterized by persistent multisystem symptoms extending beyond the acute infection phase. While respiratory and cardiac complications have received substantial clinical attention, the neurological and psychiatric sequelae remain inadequately characterized at a global scale. This study consolidates epidemiological data from 2021-2024 spanning multiple countries and regions to establish a comprehensive prevalence map of neurological and psychiatric symptoms in Long COVID populations. A systematic review of published prevalence studies and open datasets identified consistent symptom patterns across geographically diverse cohorts. Key findings reveal brain fog (cognitive impairment) as the most prevalent symptom (32-60% across populations, with Colombia reporting 60%), follow...

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