Multi-State Random Survival Forest Analysis of GVHD Trajectories

Multi-State Random Survival Forest (MS-RSF) Analysis for GVHD Trajectories

Description:
This repository contains the R script used to conduct the Multi-State Random Survival Forest (MS-RSF) analysis evaluating the impact of graft-versus-host disease (GVHD) subtypes on relapse and non-relapse mortality.

Files:
MSRSF_GVHD_Analysis.R: The main analysis script.

Data Availability:
We used publicly available dataset provided by the Center for International Blood and Marrow Transplant Research (CIBMTR) originally used in the referenced publication [Mehta et al, Transplant Cell Ther. 2025 Sep;31(9):680-692].

Requirements:
R version 4.0+, and the following packages: dplyr, survival, ggplot2, scales, parallel, randomForestSRC, tidyr, patchwork.