Bibliometric Analysis On Non-Invasive Prenatal Testing

Aim: The study aimed to analyze and assess the
global research development, collaborative network,
prestigious literature and tendency of themes about
Non-invasive prenatal testing(SDisease) (NIPT).
Material and Method: A total of 1639 scientific
publications between the years 2011-2025 were
examined in this study from the Web Science (WoS)
database databases. Country and institutional
collaborations, co-citation networks, and keyword
collocations were visualized for the data analysis in
VOSviewer.
Results: The publications in the area of NIPT were found
to have increased over years. The PR China ranked the first
both in terms of publications (n=384), with United States
of America and United Kingdom being the countries
with most significant international collaboration
networks included respectively (n=206) and (n=199). The
journal Prenatal Diagnosis contributed most, with 171
publications and 4,243 citations. Results Analysis of the
Keywords showed that research interest has shifted from
simple aneuploidy screening to technical (fetal fraction,
mosaicism and next-generation sequencing) as well as
social aspects (genetic counseling and ethical issues).
Conclusion: The NIPT field is a very active and mature
area of research with an increasing volume of interest.
The People’s Republic of China is the largest volume
contributor, US and UK are in the hub of international
collaboration and scientific influence. The emphasis
in the field has changed from pure screening to more
challenging issues like fetal fraction, mosaicism, genetic
counseling and ethics.