Published March 25, 2026 | Version v1
Dataset Open

ASSESSMENT OF THE CLINICAL COURSE OF POLYCYSTIC OVARY SYNDROME IN WOMEN OF REPRODUCTIVE AGE

  • 1. Andijan State Medical Institute

Description

Polycystic Ovary Syndrome (PCOS) is a common endocrine disorder affecting women of reproductive age and is associated with reproductive, metabolic, and hormonal disturbances. This study aimed to assess the clinical course of PCOS by analyzing its manifestations, hormonal profiles, and metabolic characteristics. The findings demonstrate that PCOS presents with heterogeneous symptoms, including menstrual irregularities, hyperandrogenism, and polycystic ovarian morphology. Insulin resistance was identified as a key factor contributing to both reproductive dysfunction and metabolic complications. Comprehensive evaluation using clinical, biochemical, and imaging methods is essential for accurate diagnosis and effective management. Early intervention and individualized treatment strategies can significantly improve patient outcomes and reduce long-term health risks.

Files

770-773.pdf

Files (196.2 kB)

Name Size Download all
md5:45bd7eb8a998b008a26daa00e669d410
196.2 kB Preview Download

Additional details

References

  • Azziz, R., Carmina, E., Chen, Z., Dunaif, A., Laven, J. S., Legro, R. S., & Yildiz, B. O. (2016). Polycystic ovary syndrome. Nature Reviews Disease Primers, 2, 16057, 1–18.
  • Rotterdam ESHRE/ASRM-Sponsored PCOS Consensus Workshop Group. (2004). Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome. Human Reproduction, 19(1), 41–47.
  • Teede, H. J., Misso, M. L., Costello, M. F., Dokras, A., Laven, J., Moran, L., & Norman, R. J. (2018). Recommendations from the international evidence-based guideline for the assessment and management of PCOS. Human Reproduction, 33(9), 1602–1618.
  • Goodarzi, M. O., Dumesic, D. A., Chazenbalk, G., & Azziz, R. (2011). Polycystic ovary syndrome: Etiology, pathogenesis, and diagnosis. Nature Reviews Endocrinology, 7(4), 219–231.
  • Diamanti-Kandarakis, E., & Dunaif, A. (2012). Insulin resistance and the polycystic ovary syndrome revisited: An update on mechanisms and implications. Endocrine Reviews, 33(6), 981–1030.