GENESIS Biohacking Pyramid: A Systems-Based Framework for Human Health Optimization

This paper introduces the GENESIS Biohacking Pyramid, a hierarchical systems-based framework for human health optimization.

The model proposes that human physiology operates through interdependent biological layers, where foundational regulation determines the effectiveness of higher-level interventions.

The framework integrates physiological metrics such as heart rate variability (HRV), sleep quality, stress response, metabolic function, and mitochondrial performance into a structured and sequential optimization model.

GENESIS provides a scalable foundation for personalized, data-driven health optimization and future integration with digital health systems and AI-driven monitoring technologies.