Published March 17, 2026 | Version 2026.03.0
Software Open

HADDOCK3 - modular integrative modelling software

  • 1. Zymvol
  • 2. @UtrechtUniversity
  • 3. Utrecht University
  • 4. Netherlands eScience center
  • 5. @haddocking
  • 6. @zymvol
  • 7. Netherlands eScience Center

Description

Bug Fixes • Fixed incorrect handling of hetero atoms during CAPRI evaluation, ensuring accurate scoring. • Corrected preprocessing when splitting structures containing MODEL records to avoid malformed inputs. • Added the correct type handling for the seed option in the random_removal command to prevent runtime errors. • Restored missing NGA glycan parameters, resolving issues with glycan-containing systems. • Added a missing example to resolve a reported workflow issue affecting several refinement modules.

Enhancements • Added automated topology/parameter generation for unknown small molecules, simplifying preparation of new ligands. • Implemented interface-ligand RMSD–based clustering for protein–ligand examples, improving analysis of docking results. • Added a runtime fallback to the local scheduler when GRID resources are unavailable, improving execution robustness.

Examples and Documentation • Added new examples demonstrating workflows and resolving previously reported usage issues. • Expanded example coverage for protein–ligand clustering workflows.

Notes

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Files

haddocking/haddock3-2026.03.0.zip

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