Published March 13, 2026
| Version 1.3.0 (Green Lizard)
Software
Open
SimulAdren
Authors/Creators
- 1. Catholic Hospitals Bochum
-
2.
Ruhr University Bochum
-
3.
Klinik Blankenstein
- 4. Lee Kong Chian School of Medicine, Nanyang Technological University Singapore
-
5.
University Hospitals of the Ruhr-University of Bochum
Description
SimulAdren is a continuous simulation program for the hypothalamus-pituitary-adrenal axis (HPA feedback control). It is based on a nonlinear MiMe-NoCoDI model and uses the CyberUnits Bricks class library.
Files
SimulAdren_V1_3_0_Handbook_and_Reference.pdf
Files
(32.0 MB)
| Name | Size | Download all |
|---|---|---|
|
md5:5ae8149ec457151a8e9b96ef9b7486a4
|
1.5 kB | Preview Download |
|
md5:cf66e1106272db81fe0c2e82feb0623a
|
3.8 MB | Preview Download |
|
md5:f138ff7e5bc2947c50c2f8c17832473c
|
8.2 MB | Preview Download |
|
md5:e62ec54765fdc83b8f95d8d17f0eb3af
|
8.9 MB | Preview Download |
|
md5:d21c288b5814fb07cf25dab67940dcfa
|
461.2 kB | Preview Download |
|
md5:7244a3381924e0ece572225848283d30
|
4.9 MB | Download |
|
md5:6529996a1fcc500ccf94507453ee7746
|
5.1 MB | Download |
|
md5:1e375ba7e44d3a31514da236c822cde0
|
659.0 kB | Preview Download |
Additional details
Related works
- Requires
- Software: 10.5281/zenodo.1304179 (DOI)
Software
- Repository URL
- https://svn.code.sf.net/p/simuladren/svn/
- Programming language
- Pascal
- Development Status
- Active
References
- Dietrich JW, Boehm BO. Equilibrium behaviour of feedback-coupled physiological saturation kinetics. In Trappl R (Editor): Cybernetics and Systems 2006. Austrian Society for Cybernetic Studies. doi: 10.13140/2.1.2400.2568
- Dietrich, JW, Boehm, BO Die MiMe-NoCoDI-Plattform: Ein Ansatz für die Modellierung biologischer Regelkreise. German Med. Sci. Abstr. 284. doi: 10.3205/15gmd s058 (2015)
- Dietrich JW. A Methodology for Vertical Translation Between Molecular and Organismal Level in Biological Feedback Loops. bioRxiv 2021.09.20.461028; doi: 10.1101/2021.09.20.461028
- Dietrich JW, Siegmar N, Hojjati JR, Gardt O, Boehm BO. CyberUnits Bricks – An Implementation Study of a Class Library for Simulating Nonlinear Biological Feedback Loops. Advances in Distributed Computing and Artificial Intelligence Journal. 2024 August; 13. doi: 10.14201/adcaij.31762